There is no doubt that not all yeasts are your friends, but this one is! Saccharomyces boulardii is a true “biotic” which has been shown to have beneficial effects by improving intestinal microbalance. Â
Specifically, S. boulardii functions in the modulation of both innate immunity by activating the complement system, and adaptive immunity by boosting the intestinal secretion of IgA. Â
In addition, S. boulardii secretes soluble factors demonstrated to reduce inflammation by lowering the NF-KappaB and mitogen-activated protein kinase (MAPK). It also enhances the secretion of mucosal factors that protect against enteric pathogens and improves tight junction structure to protect against leaky gut.Â
A couple of very practical uses of S. boulardii are to use with antibiotics (natural or pharmaceutical) to protect against antibiotic-related diarrhea, and also when traveling to protect against traveler’s diarrhea. And, of course, because of its anti-inflammatory properties, it should be considered for anyone with inflammatory bowel conditions.Â
One of the very interesting properties of S. boulardii is that oral administration achieves a steady state concentration within three days but it does not colonize the intestinal tract. Typically, it will be cleared from the intestines within 2 to 5 days after discontinuing use. Therefore, S. boulardii is a very useful yeast indeed! Â
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